type 2 diabetes
While doing some online research about blood sugar control and type 2 diabetes I ran across an article written by Patrick J. Skerrett and posted on the Harvard Health Blog. Mr. Skerrett was describing his participation in a recent study where the final results are now posted by ClinicalTrials.gov.
Needless to say, it got me to thinking. I was diagnosed with type 2 diabetes more than thirty years ago and have basically used a reasonable diet and exercise to control my blood sugar without taking any diabetic based medication.
However, during this time period, I either took plain old aspirin or Naproxen Sodium an aspirin based drug used to control inflammation. They were prescribed by my health care giver to reduce the pain and inflammation for a hip injury I received in a car accident.
The particular drug targeted in the study is SALsalate another aspirin based drug. Since the study seems to show that participants in the study benefited with lower blood sugar levels even though many of them also had an average weight gain of approximately 2 pounds, I began to wonder if my efforts to control my blood sugar levels using just a diet and exercise had been secretly assisted by my use of aspirin and Naproxen Sodium.
I continue to take the Naproxen daily, always making sure to take it with food and even with those precautions, I have had two lesions removed from my colon.
No one directly advised me to stop taking the Naproxen, didn’t even relate it to the lesions, but since digestive problems are listed as a side effect for this drug….it got me to thinking, so I did some research which I listed below in study information.
The stated purpose of the study was stated as follows:
Growing evidence over recent years supports a potential role for low grade chronic inflammation in the pathogenesis of insulin resistance and type 2 diabetes. In this study we will determine whether salsalate, a member of the commonly used Non-Steroidal Anti-Inflammatory Drug (NSAID) class, is effective in lowering sugars in patients with type 2 diabetes. The study will determine whether salicylates represent a new pharmacological option for diabetes management. The study is conducted in two stages. The primary objective of the first stage is to select a dose of salsalate that is both well-tolerated and demonstrates a trend toward improvement in glycemic control. The primary objective of Stage 2 of the study is to evaluate the effects of salsalate on blood sugar control in diabetes; the tolerability of salsalate use in patients with type 2 diabetes (T2D); and the effects of salsalate on measures of inflammation, the metabolic syndrome, and cardiac risk.”
For your convenience the recently released report is available at Targeting INflammation Using SALsalate in Type 2 Diabetes (TINSAL-T2D)
I plan to call my caregiver and discuss this study and ask if I should be taking salsalate which seems to have fewer or no digestive upsets instead of the one I a now taking.
Since it is now 6:15 a.m. and she isn’t in her office, I’ll have to update later and reveal her recommendation.
Sometimes we get lucky and do things almost right! For my own information, I did a search on WikipediA and found this excerpt from an article:
“Salsalate is used to reduce pain and inflammation caused by conditions such as rheumatoid arthritis, osteoarthritis, and related rheumatic conditions. Salsalate is also recommended by physicians as an anti-inflammatory alternative to naproxen, and ibuprofen for patients that have had minor stomach bleeding or stomach upset. It has also been used as an alternative to narcotic pain medicine for people with spinal disc protrusion.” Read complete article by clicking on the link below.
There is still a side effect on this drug related to the digestive system, so I’m not sure if changing what I’m taking will make a difference, but the positive is that there is documented information that indicates that there is a positive result when taking this drug to control inflammation for people with or without diabetes….suggesting that it helps reduce blood sugar and may even work as a pre-diabetes preventer.
For more information, I’d suggest reading the WikipediA article..many of the references cited there are unavailable to be listed here. Will Taking Salsalate Help control blood sugar Levels in Type 2 Diabetics
When you have diabetes it is always important to continue learning about diabetes.
Self Education should be part of regimen to control your blood sugar right along with your sugar control diet and exercise.
I still believe that You are What You Eat……..